NewslettersDermal Cell News A Unique Hyperdynamic Dimer Interface Permits Small Molecule Perturbation of the Melanoma Oncoprotein MITF for Melanoma Therapy By Laurisa Dohm - January 9, 2023 0 Using chromatin immunoprecipitation assay and RNA sequencing, scientists showed that compound TT-012 inhibited the transcriptional activity of microphthalmia transcription factor (MITF) in B16F10 melanoma cells. [Cell Research] Abstract