NewslettersOrganoid NewsPancreatic Cell News Targeting Src Reactivates Pyroptosis to Reverse Chemoresistance in Lung and Pancreatic Cancer Models By lbeveridge - January 12, 2023 0 Researchers demonstrated that β5-integrin repressesed chemotherapy-induced canonical pyroptosis to confer cancer chemoresistance through ASAH2-driven sphingolipid metabolic reprogramming. [Science Translational Medicine] Abstract