NewslettersPancreatic Cell News The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo By Bob - March 14, 2023 0 To identify how loss of Chd4 impacts glucose homeostasis and gene expression programs in β-cells in vivo, researchers generated an inducible-β-cell-specific Chd4 knockout mouse model. [Diabetes] Abstract