NewslettersHepatic Cell News Integrated Analysis Revealing the Role of TET3-Mediated MUC13 Promoter Hypomethylation in Hepatocellular Carcinogenesis By Bob - March 17, 2023 0 MUC13 was upregulated in HCC and liver cancer stem cells (CSCs) and had a positive influence on CSC generation. Further analyses revealed that MUC13 with promoter hypomethylated was regulated by DNA demethylase TET3. [Epigenomics] Abstract