NewslettersCancer Stem Cell News Abrogation of Stemness in Osteosarcoma by the Mithramycin Analog EC-8042 Is Mediated by Its Ability to Inhibit NOTCH-1 Signaling By Noshin Noorjahan - April 12, 2023 0 In transcriptomic and protein expression analyses, scientists identified NOTCH1 signaling as one of the main pro-stemness pathways repressed by EC-8042 in osteosarcomas. [Biomedicine & Pharmacotherapy] Full Article