NewslettersHematopoiesis News Transcription Factor Nkx2-3 Maintains the Self-Renewal of Hematopoietic Stem Cells by Regulating Mitophagy By Jamie Kang - May 1, 2023 0 Scientists showed that the homeobox transcription factor Nkx2-3 was required for HSC self-renewal by preserving metabolic fitness. They found that Nkx2-3 was preferentially expressed in HSCs with excessive regenerative potential. [Leukemia] Abstract