Home Newsletters Cancer Stem Cell News p140Cap Inhibits β-Catenin in the Breast Cancer Stem Cell Compartment Instructing a...

p140Cap Inhibits β-Catenin in the Breast Cancer Stem Cell Compartment Instructing a Protective Anti-Tumor Immune Response

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Integrative transcriptomic and preclinical studies unraveled that p140Cap controlled an epistatic axis where, through the upstream inhibition of β-Catenin, it restricted tumorigenicity and self-renewal of tumor-initiating cells.
[Nature Communications]
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