NewslettersImmune Regulation News IL-21 Shapes Germinal Center Polarization via Light Zone B Cell Selection and Cyclin D3 Upregulation By Laurisa Dohm - July 28, 2023 0 The authors showed that IL-21, the archetypal follicular helper T cell cytokine, shaped the scale and polarization of spontaneous chronic autoimmune as well as transient immunization-induced germinal center. [Journal Of Experimental Medicine] Full Article