NewslettersProstate Cell News Lysosome-Dependent FOXA1 Ubiquitination Contributes to Luminal Lineage of Advanced Prostate Cancer By Noshin Noorjahan - July 28, 2023 0 Researchers showed that S-phase kinase-associated protein 2 (SKP2) catalyzed K6- and K29-linked polyubiquitination of forkhead box protein A1 (FOXA1) for lysosomal-dependent degradation. [Molecular Oncology] Abstract