Hexokinase 2 Confers Radio-Resistance in Hepatocellular Carcinoma by Promoting Autophagy-Dependent Degradation of AIMP2

Researchers confirmed the upregulation of hexokinase 2 (HK2) in HCC tissue and demonstrated that HK2 exerteed a radio-resistant role by attenuating apoptosis and promoting proliferation in HCC cell lines.