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IL-6 Trans-Signaling in a Humanized Mouse Model of Scleroderma

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Investigators tested whether the MISTRG6 strain of humanized mice could be transplanted with healthy or scleroderma human skin grafts. They found that healthy and scleroderma skin grafts retained skin and bone marrow–derived immune cells.
[Proceedings Of The National Academy Of Sciences Of The United States Of America]
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