NewslettersImmune Regulation News The PTPN2/PTPN1 Inhibitor ABBV-CLS-484 Unleashes Potent Anti-Tumor Immunity By Laurisa Dohm - October 6, 2023 0 The authors showed that AC484 inflamed the tumor microenvironment and promoted natural killer cell and CD8+ T cell function by enhancing JAK–STAT signalling and reducing T cell dysfunction. [Nature] Full ArticlePress Release