NewslettersDermal Cell News Inhibition of TGF-β Signaling, Invasion, and Growth of Cutaneous Squamous Cell Carcinoma by PLX8394 By Laurisa Dohm - October 23, 2023 0 Investigators showed that the next-generation B-Raf inhibitor PLX8394 blocked TGF-β signaling in ras-transformed metastatic epidermal keratinocytes harboring wild-type B-Raf and hyperactive Ras. [Oncogene] Full Article