NewslettersPancreatic Cell News The Lin28b/Wnt5a Axis Drives Pancreas Cancer Through Crosstalk Between Cancer Associated Fibroblasts and Tumor Epithelium By Bob - October 31, 2023 0 Investigators showed that Lin28b/let-7 pathway was indispensable for modulating the expression of Wnt5a in tumor epithelium, which could be secreted and then up-regulated Lin28b in cancer-associated fibroblasts. [Nature Communications] Full Article