NewslettersCancer Stem Cell NewsHematopoiesis News Stem Cell–Like Reprogramming Is Required for Leukemia-Initiating Activity in B-ALL By Bob - November 7, 2023 0 Researchers used the PAX5::ELN oncogenic model to demonstrate a causal link between the differentiation blockade, the self-renewal, and the emergence of pre-leukemic stem cells. [Journal of Experimental Medicine] Abstract