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The Dopamine Transporter Antagonist Vanoxerine Inhibits G9a and Suppresses Cancer Stem Cell Functions in Colon Tumors

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Using a stem cell-based phenotypic drug-screening pipeline, the authors identified the dopamine transporter antagonist vanoxerine, a compound with previously demonstrated clinical safety, as a cancer-specific downregulator of G9a expression.
[Nature Cancer]
Abstract
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