NewslettersCancer Stem Cell News Lactate-Driven Type I Collagen Deposition Facilitates Cancer Stem Cell-Like Phenotype of Head and Neck Squamous Cell Carcinoma By lbeveridge - March 4, 2024 0 Scientists found that lactate increased CSC characteristics of head and neck squamous cell carcinoma by influencing the deposition of type I collagen (Col I). Lactate promoted Col I deposition through two distinct pathways. [iScience] AbstractGraphical Abstract