NewslettersMammary Cell News Nuclear Localization of Heparanase 2 (Hpa2) Attenuates Breast Carcinoma Growth and Metastasis By Emily Salmini - March 22, 2024 0 The authors discovered that overexpression of Hpa2 in breast carcinoma cells resulted in bigger tumors, whereas targeting Hpa2 to the cell nucleus attenuated tumor growth and tumor metastasis. [Cell Death & Disease] Full Article