Treatment with Tideglusib alone and in combination with radiation significantly decreased the colony formation of U-251 MG cells and the sphere formation of both cell lines, by targeting and reducing their glioblastoma cancer stem-like cells population.
[Pharmacological Reports]
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Bou-Gharios, J., Assi, S., Bahmad, H. F., Kharroubi, H., Araji, T., Chalhoub, R. M., Ballout, F., Harati, H., Fares, Y., & Abou-Kheir, W. (2020). The potential use of tideglusib as an adjuvant radio-therapeutic treatment for glioblastoma multiforme cancer stem-like cells. Pharmacological Reports. https://doi.org/10.1007/s43440-020-00180-5 Cite
