Glioblastoma cells that are part of the tumor microtube-connected tumor network showed activated neurodevelopmental and glioma progression gene expression pathways. Importantly, many of them revealed profiles indicative of increased cellular stemness, including high expression of nestin.
[Neuro-Oncology]
6807162
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Xie, R., Kessler, T., Grosch, J., Hai, L., Venkataramani, V., Huang, L., Hoffmann, D. C., Solecki, G., Ratliff, M., Schlesner, M., Wick, W., & Winkler, F. (2020). Tumor cell network integration in glioma represents a stemness feature. Neuro-Oncology, noaa275. https://doi.org/10.1093/neuonc/noaa275 Cite
