Researchers report that Piwi-like family members were overexpressed in glioblastoma, with Piwil1 most frequently overexpressed. Piwil1 was enriched in glioma stem-like cells to maintain self-renewal.
[Cell Reports]
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Huang, H., Yu, X., Han, X., Hao, J., Zhao, J., Bebek, G., Bao, S., Prayson, R. A., Khalil, A. M., Jankowsky, E., & Yu, J. S. (2021). Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression. Cell Reports, 34(1). https://doi.org/10.1016/j.celrep.2020.108522 Cite
