The authors identified CD93 as an important regulator of self-renewal and proliferation of murine and human leukemia stem cells, but not hematopoietic stem cells.
[Cell Reports]
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Riether, C., Radpour, R., Kallen, N. M., Bürgin, D. T., Bachmann, C., Schürch, C. M., Lüthi, U., Arambasic, M., Hoppe, S., Albers, C. E., Baerlocher, G. M., & Ochsenbein, A. F. (2021). Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells. Cell Reports, 34(4). https://doi.org/10.1016/j.celrep.2020.108663 Cite
