Researchers demonstrated greater expression of TMCC3 in breast cancer stem cells (BCSCs) than non-BCSCs and higher expression of TMCC3 in metastatic lymph nodes and lungs than in primary tumor of breast cancer patient-derived xenograft.
[Oncogene]
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Wang, Y.-H., Chan, Y.-T., Hung, T.-H., Hung, J.-T., Kuo, M.-W., Wang, S.-H., Huang, Y., Lin, Y.-J., Chen, S.-C., Yu, J.-C., Wu, J.-C., Yu, J., & Yu, A. L. (2021). Transmembrane and coiled-coil domain family 3 (TMCC3) regulates breast cancer stem cell and AKT activation. Oncogene, 1–14. https://doi.org/10.1038/s41388-021-01729-1 Cite
