Scientists report that TWIST1, an epithelial-to-mesenchymal transition (EMT) regulated by transcription factors, exhibited positive transcriptional regulation on PDGFRβ promoter, thus identifying PDGFRβ as one of the downstream targets of EMT regulation in breast CSCs.
[Biochimica Et Biophysica Acta-Molecular Basis of Disease]
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Yeeravalli, R., Kaushik, K., & Das, A. (2021). TWIST1-mediated transcriptional activation of PDGFRβ in breast cancer stem cells promotes tumorigenesis and metastasis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 166141. https://doi.org/10.1016/j.bbadis.2021.166141 Cite
