The authors describe a powerful seven day HSC hibernation culture system that maintained HSCs as single cells in the absence of a physical niche.
[Stem Cell Reports]
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Oedekoven, C. A., Belmonte, M., Bode, D., Hamey, F. K., Shepherd, M. S., Che, J. L. C., Boyd, G., McDonald, C., Belluschi, S., Diamanti, E., Bastos, H. P., Bridge, K. S., Göttgens, B., Laurenti, E., & Kent, D. G. (2021). Hematopoietic stem cells retain functional potential and molecular identity in hibernation cultures. Stem Cell Reports, 0(0). https://doi.org/10.1016/j.stemcr.2021.04.002 Cite
