Home Newsletters Cancer Stem Cell News PELP1/Src-3-Dependent Regulation of Metabolic Pfkfb Kinases Drives Therapy Resistant Er+ Breast Cancer

PELP1/Src-3-Dependent Regulation of Metabolic Pfkfb Kinases Drives Therapy Resistant Er+ Breast Cancer

By
Justin.choi
-
0
Researchers showed that cytoplasmic complexes composed of steroid receptor co-activators, PELP1 and SRC-3, modulated breast cancer stem cell expansion through upregulation of the HIF-activated metabolic target genes PFKFB3 and PFKFB4.
[Oncogene]
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Abstract

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