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AKT Inhibitor AZD5363 Suppresses Stemness and Promotes Anti-Cancer Activity of 3,3′-Diindolylmethane in Human Breast Cancer Cells

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Investigators observed that proportion of CD133+Nanog+ subpopulation in MCF-7 cells was significantly increased after 3,3′-diindolylmethane administration with up-regulated AKT activity by using CyTOF assay.
[Toxicology and Applied Pharmacology]

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