Using synthetic hyaluronic acid hydrogels as a chemically and mechanically tunable system to preserve lymphatic endothelial cell phenotypes, scientists demonstrated that low matrix elasticity primed lymphatic cord‐like structure formation directed by a high concentration of vascular endothelial growth factor‐C (VEGF‐C).
[FASEB Journal]
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Alderfer, L., Russo, E., Archilla, A., Coe, B., & Hanjaya‐Putra, D. (2021). Matrix stiffness primes lymphatic tube formation directed by vascular endothelial growth factor-C. The FASEB Journal, 35(5), e21498. https://doi.org/https://doi.org/10.1096/fj.202002426RR Cite
