Researchers suggested that Scutellarin reduced triple-negative breast cance metastasis by suppressing tumor necrosis factor-α (TNFα)-initiated vascular endothelial barrier breakdown through rescuing the reduced expression of junctional proteins by regulating the TNF receptor 2-extracellular signal-regulated protein kinase1/2-enhancer of zeste homolog-2 signaling pathway.
[Acta Pharmacologica Sinica]
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