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Impact of α-Synuclein Pathology on Transplanted hESC-Derived Dopaminergic Neurons in a Humanized α-Synuclein Rat Model of PD

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Researchers established a humanized transplantation model of Parkinson’s disease that better recapitulates the main disease features, obtained by coinjection of preformed human α-synuclein (α-syn) fibrils and adeno-associated virus expressing human wild-type α-syn unilaterally into the rat substantia nigra.
[Proceedings of the National Academy of Sciences of the United States of America]
6445212 {6630899:AE8ZEQJC} apa 50 1 150799 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
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