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Neuronal Mitochondrial Dysfunction in Sporadic Amyotrophic Lateral Sclerosis Is Developmentally Regulated

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Scientists used human iPSCs and generated a developmental timeline by differentiating sporadic amyotrophic lateral sclerosis (sALS) iPSCs to neural progenitors and to motor neurons and comparing mitochondrial parameters with familial ALS and control cells at each developmental stage.
[Scientific Reports]
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