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Human Pluripotent Stem-Cell-Derived Islets Ameliorate Diabetes in Non-Human Primates

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Researchers generated islets from human chemically induced PSCs (hCiPSC-islets) and showed that a one-dose intraportal infusion of hCiPSC-islets into diabetic non-human primates effectively restored endogenous insulin secretion and improved glycemic control.
[Nature Medicine]
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