The biological capacity of lncRNA named lncRNA activated in metastatic PCa (lncAMPC) in prostate cancer (PCa) was demonstrated both in vitro and in vivo. The lncAMPC was overexpressed in tumor tissue and urine of metastatic PCa patients and promoted PCa tumorigenesis and metastasis.
[Molecular Therapy]
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Zhang, W., Shi, X., Chen, R., Zhu, Y., Peng, S., Chang, Y., … Ren, S. (2020). Novel long non-coding RNA lncAMPC promotes metastasis and immunosuppression in prostate cancer by stimulating LIF/LIFR expression. Molecular Therapy, 0(0). https://doi.org/10.1016/j.ymthe.2020.06.013 Cite
