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A Variant in IL6ST with a Selective IL-11 Signaling Defect in Human and Mouse

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Researchers characterized the impact of a variant on cytokine signaling in vitro using transfected cell lines as well as primary patient-derived cells and supported these findings using a mouse model with the corresponding genome-edited variant Il6st p.R279Q.
[Bone Research]
6445212 {6445212:FX8U385D} apa 50 1 150762 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
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