An inert form of the human NKG2D extracellular domain (iNKG2D) was engineered as the ectodomain of the chimeric antigen receptor (CAR) to generate convertibleCARTM-T cells. These cells were specifically directed to kill antigen-expressing target cells only in the presence of an activating bispecific adapter comprised of an iNKG2D-exclusive ULBP2-based ligand fused to an antigen-targeting antibody
[Communications Biology]
6445212
{6445212:NUJ36NDU}
apa
50
1
150772
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