Researchers identified microRNA-146a as a major negative regulator of colonic inflammation and associated tumorigenesis by modulating IL-17 responses.
[Nature Communications]
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Garo, L. P., Ajay, A. K., Fujiwara, M., Gabriely, G., Raheja, R., Kuhn, C., Kenyon, B., Skillin, N., Kadowaki-Saga, R., Saxena, S., & Murugaiyan, G. (2021). MicroRNA-146a limits tumorigenic inflammation in colorectal cancer. Nature Communications, 12(1), 2419. https://doi.org/10.1038/s41467-021-22641-y Cite
