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Lineage Reversion Drives WNT Independence in Intestinal Cancer

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Scientists showed that while WNT suppression blocked tumor growth in most organoid and in vivo colorectal cancer (CRC) models, the accumulation of CRC-associated genetic alterations enabled drug resistance and WNT-independent growth.
[Cancer Discovery]
6445212 {6606345:4HPBCCA2} apa 50 1 150943 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
Abstract
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