Home Newsletters Intestinal Cell News Discovery of New Anticancer Thiourea-Azetidine Hybrids: Design, Synthesis, In Vitro Antiproliferative, SAR,...

Discovery of New Anticancer Thiourea-Azetidine Hybrids: Design, Synthesis, In Vitro Antiproliferative, SAR, In Silico Molecular Docking against VEGFR-2, ADMET, Toxicity, and DFT Studies

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Synthesized compounds were evaluated for their in vitro anticancer activity against various human cancer cell lines, including breast and prostate.
[Bioorganic Chemistry]
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Parmar, D. R., Soni, J. Y., Guduru, R., Rayani, R. H., Kusurkar, R. V., Vala, A. G., Talukdar, S. N., Eissa, I. H., Metwaly, A. M., Khalil, A., Zunjar, V., & Battula, S. (2021). Discovery of new anticancer thiourea-azetidine hybrids: design, synthesis, in vitro antiproliferative, SAR, in silico molecular docking against VEGFR-2, ADMET, toxicity, and DFT studies. Bioorganic Chemistry, 115, 105206. https://doi.org/10.1016/j.bioorg.2021.105206 Cite
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