While cyclin-dependent kinase 1 (CDK1) phosphorylation is a well-described consequence of temozolomide (TMZ) treatment, researchers found that TMZ also robustly induced CDK1 expression.
[Scientific Reports]
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Voce, D. J., Bernal, G. M., Cahill, K. E., Wu, L., Mansour, N., Crawley, C. D., Campbell, P.-A. S., Arina, A., Weichselbaum, R. R., & Yamini, B. (2021). CDK1 is up-regulated by temozolomide in an NF-κB dependent manner in glioblastoma. Scientific Reports, 11(1), 5665. https://doi.org/10.1038/s41598-021-84912-4 Cite
