NewslettersPancreatic Cell News ISL2 Is a Putative Tumor Suppressor Whose Epigenetic Silencing Reprograms the Metabolism of Pancreatic Cancer By Britya Ghosh - May 10, 2022 0 Through in vivo CRISPR screening, scientists discovered islet-2 (ISL2) as a candidate tumor suppressor that modulates aggressive PDAC growth. [Developmental Cell] AbstractGraphical Abstract