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Pulmonary Cell NewsAll Articles by Author:
Britya Ghosh
Cancer Stem Cell News
Disruption of β-Catenin-Mediated Negative Feedback Reinforces cAMP-Induced Neuronal Differentiation in Glioma Stem Cells
[Cell Death & Disease] Scientists demonstrated that cAMP triggered neuronal differentiation and compromised the self-renewal capacity in glioma stem cells.
Cancer Stem Cell News
GSK3β Palmitoylation Mediated by ZDHHC4 Promotes Tumorigenicity of Glioblastoma Stem Cells in Temozolomide-Resistant Glioblastoma through the EZH2–STAT3 Axis
[Oncogenesis] Researchers found that GSK3β was noted as a substrate for ZDHHC4-mediated palmitoylation at the Cys14 residue, which enhanced glioblastoma temozolomide resistance and glioblastoma stem cell self-renewal.
Cancer Stem Cell News
ΔNp63α Mediates Sulforaphane Suppressed Colorectal Cancer Stem Cell Properties through Transcriptional Regulation of Nanog/Oct4/Sox2
[Journal of Nutritional Biochemistry] Scientists showed that ΔNp63α expression was enhanced in sphere-forming colorectal cancer cells.
Cancer Stem Cell News
Identification of Two Cancer Stem Cell-Like Populations in Triple-Negative Breast Cancer Xenografts
[Disease Models & Mechanisms] The multiple-microtissue transcriptome analysis revealed three cancer cell-type clusters in the primary tumor and axillary lymph node metastasis, two of which were CSC-like clusters.
Cancer Stem Cell News
GM-CSF-miRNA-Jak2/Stat3 Signaling Mediates Chemotherapy-Induced Cancer Cell Stemness in Gastric Cancer
[Frontiers in Pharmacology] Researchers treated two human gastric cancer cell lines SGC7901 and BGC823 with 5-Fluorouracil or Cisplatin in vitro.
Cancer Stem Cell News
Recombinant Expression a Novel Fibronectin—Collage Fusion Peptide Modulating Stem Cell Stemness via Integrin β3
[Applied Microbiology and Biotechnology] A novel recombinant protein fibronectin-collagen peptide was designed to modulate the function of extracellular matrix expressed by Picha. pastoris strain X33.
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Downregulation of Mirlet7 miRNA Family Promotes Tc17 Differentiation and Emphysema via De-repression of RORγt
[eLife] The authors demonstrated that loss of the Mirlet7b/Mirlet7c2 cluster in T cells predisposed mice to exaggerated cigarette smoke- or nanosized carbon black-elicited emphysema.
Iron Overload–Dependent Ferroptosis Aggravates LPS-Induced Acute Lung Injury by Impairing Mitochondrial Function
[Inflammation] Investigators observed a significant increase in iron concentration during acute lung injury, accompanied by elevated levels of lipid peroxidation markers such as malonaldehyde and 4-hydroxynonenal.
Sfrp5 Overexpression Reverses oxLDL-Induced Lipid Accumulation in HVSMCs
[Bioscience, Biotechnology, and Biochemistry] Researchers found that Sfrp5 expression in oxLDL-treated human vascular smooth muscle cells (HVSMCs) was downregulated. Sfrp5 overexpression inhibited the viability of HVSMCs induced by oxLDL.
