Category Archives: Dermal Cell

Dermal Cell News is an online publication and email newsletter highlighting the latest research about wound healing, skin disorders, and dermal cancers.
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As the largest organ in the human body, the skin is implicated in a wide range of health conditions. Dermal Cell News is dedicated to covering it all. Our website, newsletter, and Twitter feed highlight research on tissue regeneration in the treatment of skin wounds, burns, cancers, and disorders. We also feature relevant job postings and upcoming events.

ASLAN Pharmaceuticals Announces Scientific Collaboration with Dr. Emma Guttman-Yassky on Identification of ASLAN004-Specific Biomarkers

ASLAN Pharmaceuticals announced a collaboration with renowned inflammatory skin disease expert Dr. Emma Guttman-Yassky to conduct research that will continue throughout ASLAN’s Phase IIb program to identify and characterize the effects of ASLAN004 on disease-associated skin and serum-biomarkers in adults with moderate-to-severe atopic dermatitis.
[ASLAN Pharmaceuticals]
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Dupixent® (Dupilumab) Is The First Biologic To Significantly Reduce Itch And Skin Lesions In Phase III Trial For Prurigo Nodularis, Demonstrating The Role Of Type 2 Inflammation In This Disease

Regeneron Pharmaceuticals, Inc. and Sanofi announced positive pivotal Phase III results from a trial evaluating Dupixent® in adults with uncontrolled prurigo nodularis, a chronic type 2 inflammatory skin disease that causes extreme itch and skin lesions.
[Regeneron Pharmaceuticals, Inc.]
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Oleuropein Multicompartment Nanovesicles Enriched with Collagen as a Natural Strategy for the Treatment of Skin Wounds Connected with Oxidative Stress

Collagen-enriched transfersomes, glycerosomes and glytransfersomes were specifically tailored by the investigators for skin delivery of oleuropein.
[Nanomedicine]
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Combining Systemic and Locally Applied Cellular Therapies for the Treatment of Systemic Sclerosis

Investigators provide an overview of the cellular therapies available for the management of systemic sclerosis, including systemically injected therapies and locally administered regenerative cell therapies.
[Bone Marrow Transplantation]
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RedDress Earns a Strategic Partnership with MediGroup

RedDress announced that it has entered into a partnership with MediGroup to deliver its innovative wound care solution, ActiGraft® system to MediGroup’s members.
[RedDress (GlobeNewsWire, Inc.)]
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Novel Scaffold Based Graphene Oxide Doped Electrospun Iota Carrageenan/Polyvinyl Alcohol for Wound Healing and Pathogen Reduction: In Vitro and In Vivo Study

Scientists worked with electrospun nanofiber scaffold named that was composed of polyvinyl alcohol/iota carrageenan and doped with partially reduced graphene oxide that was successfully synthesized for wound healing and skin repair.
[Scientific Reports]
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Building and Maintaining the Skin

Investigators review diverse cellular interactions and highlight how far-reaching signals can be transmitted at the local level to enable skin stem cells to tailor their actions to suit the particular occasion and optimize fitness.
[Cold Spring Harbor Perspectives in Biology]
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Insight into the Role of Dermal White Adipose Tissue Loss in Dermal Fibrosis

The authors indicate that the adipocytes-to-myofibroblasts transition in dermal white adipose tissue reflects the direct contribution to the dermal fibrosis formation
[Journal of Cellular Physiology]
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Krystal Biotech and GeneDx Announce Collaboration to Provide No-Charge Genetic Testing for Patients with Suspected Dystrophic Epidermolysis Bullosa (DEB)

Krystal Biotech, Inc. and GeneDx, Inc. announced a collaboration offering no-charge genetic testing for all types of Epidermolysis Bullosa.
[Krystal Biotech, Inc.]
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Hair Shaft Miniaturization Causes Stem Cell Depletion through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis

Investigators demonstrated that hair shaft loss or a reduction in diameter shrunk the physical niche size, which resulted in mechanical compression of hair follicle stem cells and their apoptotic loss.
[Cell Stem Cell]
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Nobiletin-Loaded Composite Penetration Enhancer Vesicles Restore the Normal miRNA Expression and the Chief Defence Antioxidant Levels in Skin Cancer

The authors loaded nobiletin in various vesicular systems to improve its cytotoxicity against skin cancer. Vesicles were prepared using the thin film hydration method, and characterized for particle size, zeta potential, entrapment efficiency, TEM, ex-vivo skin deposition and physical stability.
[Scientific Reports]
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