Oleuropein Multicompartment Nanovesicles Enriched with Collagen as a Natural Strategy for the Treatment of Skin Wounds Connected with Oxidative Stress

Collagen-enriched transfersomes, glycerosomes and glytransfersomes were specifically tailored by the investigators for skin delivery of oleuropein.
[Nanomedicine]
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Combining Systemic and Locally Applied Cellular Therapies for the Treatment of Systemic Sclerosis

Investigators provide an overview of the cellular therapies available for the management of systemic sclerosis, including systemically injected therapies and locally administered regenerative cell therapies.
[Bone Marrow Transplantation]
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RedDress Earns a Strategic Partnership with MediGroup

RedDress announced that it has entered into a partnership with MediGroup to deliver its innovative wound care solution, ActiGraft® system to MediGroup’s members.
[RedDress (GlobeNewsWire, Inc.)]
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Novel Scaffold Based Graphene Oxide Doped Electrospun Iota Carrageenan/Polyvinyl Alcohol for Wound Healing and Pathogen Reduction: In Vitro and In Vivo Study

Scientists worked with electrospun nanofiber scaffold named that was composed of polyvinyl alcohol/iota carrageenan and doped with partially reduced graphene oxide that was successfully synthesized for wound healing and skin repair.
[Scientific Reports]
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Building and Maintaining the Skin

Investigators review diverse cellular interactions and highlight how far-reaching signals can be transmitted at the local level to enable skin stem cells to tailor their actions to suit the particular occasion and optimize fitness.
[Cold Spring Harbor Perspectives in Biology]
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Insight into the Role of Dermal White Adipose Tissue Loss in Dermal Fibrosis

The authors indicate that the adipocytes-to-myofibroblasts transition in dermal white adipose tissue reflects the direct contribution to the dermal fibrosis formation
[Journal of Cellular Physiology]
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Krystal Biotech and GeneDx Announce Collaboration to Provide No-Charge Genetic Testing for Patients with Suspected Dystrophic Epidermolysis Bullosa (DEB)

Krystal Biotech, Inc. and GeneDx, Inc. announced a collaboration offering no-charge genetic testing for all types of Epidermolysis Bullosa.
[Krystal Biotech, Inc.]
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Hair Shaft Miniaturization Causes Stem Cell Depletion through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis

Investigators demonstrated that hair shaft loss or a reduction in diameter shrunk the physical niche size, which resulted in mechanical compression of hair follicle stem cells and their apoptotic loss.
[Cell Stem Cell]
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Nobiletin-Loaded Composite Penetration Enhancer Vesicles Restore the Normal miRNA Expression and the Chief Defence Antioxidant Levels in Skin Cancer

The authors loaded nobiletin in various vesicular systems to improve its cytotoxicity against skin cancer. Vesicles were prepared using the thin film hydration method, and characterized for particle size, zeta potential, entrapment efficiency, TEM, ex-vivo skin deposition and physical stability.
[Scientific Reports]
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Molecular Characterization of Biphenotypic Epithelioid and Plexiform Melanoma with Deep Penetrating Nevus (DPN)-Like Features

Scientists investigated a case of melanoma that displayed a dual phenotype: a DPN-like/plexiform portion in conjunction with a conventional epithelioid morphology.
[Pigment Cell & Melanoma Research]
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Lixte Biotechnology Announces Collaboration with Netherlands Cancer Institute (Amsterdam) and Oncode Institute (Utrecht) to Identify the Most Promising Drug Combinations for its Lead Clinical Compound, LB-100, for Cancer Treatment

Lixte Biotechnology Holdings, Inc. announced entry into a collaboration with the Netherlands Cancer Institute, Amsterdam, and Oncode Institute, Utrecht to identify the most promising drugs to be combined with LB-100, and potentially LB-100 analogues, to be used to treat a range of cancers, as well as to identify the specific molecular mechanisms underlying the identified combinations.
[Lixte Biotechnology Holdings, Inc.]
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