Prostate Cell News

Prostate Cell News is an online resource summarizing the latest prostate cell research.

£1 Million Funding Award Supports Leading New Medical Research at Northumbria University

[Northumbria University] Two renowned biomedical researchers have been awarded £1 million to undertake world-leading research into diseases such as prostate cancer and mitochondrial disease at Northumbria University.

Suppression of Tumor Cell Lactate-Generating Signaling Pathways Eradicates Murine PTEN/p53-Deficient Aggressive-Variant Prostate Cancer via Macrophage Phagocytosis

[Clinical Cancer Research] Scientists targeted immunometabolic mechanisms of PI3Ki resistance, with the goal of durable tumor control in aggressive-variant prostate cancer.

Reciprocal Negative Feedback Regulation of ATF6α and PTEN Promotes Prostate Cancer Progression

[Cellular and Molecular Life Sciences] The authors demonstrated that the expression level of phosphatase and tensin homolog (PTEN) was inversely correlated with the signature score of unfolded protein response in prostate cancer.

RNA Interference Against ATP as a Gene Therapy Approach for Prostate Cancer

[Molecular Pharmaceutics] Researchers developed an RNA interference method against adenosine triphosphate (ATP) by constructing an interfering plasmid-expressing ATP-binding RNA aptamer, which notably inhibited the growth of prostate cancer cells through diminishing the availability of cytoplasmic ATP.

Selenium in Combination With a Tomato Lipid Extract as a Therapy for Benign Prostatic Hyperplasia and Its Alterations in Rats With Induced BPH

[Journal of Cellular and Molecular Medicine] The authors evaluated the therapeutic effect of selenium in combination with a tomato extract in aged rats with benign prostatic hyperplasia (BPH).

The Effect of Acupuncture on Estrogen Receptors in Rats With Benign Prostatic Hyperplasia

[Journal of Steroid Biochemistry and Molecular Biology] Scientists elucidated the effects of acupuncture on the protein and gene expression of estrogen receptors alpha and beta in testosterone-induced benign prostatic hyperplasia in rat models.

Tumor-Microenvironment Responsive Nano-Carrier System for Therapy of Prostate Cancer

[Journal Of Materials Science-Materials In Medicine] Experiments in vitro showed that DTX-loaded poly-Tetraethylene glycol nanoparticles had good compatibility to healthy cells and strong anti-tumor effect.

Doxorubicin-Induced Senescence Promotes Resistance to Cell Death by Modulating Genes Associated With Apoptotic and Necrotic Pathways in Prostate Cancer DU145 CD133+/CD44+ Cells

[Biochemical and Biophysical Research Communications] Investigators elucidated the effects of senescence induction on proliferation, cell cycle, and apoptosis in prostate cancer stem cells (CSCs) and non-CSCs.

A Crosstalk Between Castration-Resistant Prostate Cancer Cells, M2 Macrophages, and NK Cells: Role of the ATM-PI3K/AKT-PD-L1 Pathway

[Immunological Investigations] Using CRPC cell lines, the transwell chamber experiments revealed ataxia telangiectasia mutant kinase (ATM) promoted macrophage recruitment in CRPC cells in vitro via C-X-C motif chemokine ligand 12.

Knocking Down SOX2 Overcomes the Resistance of Prostate Cancer to Castration via Notch Signaling

[Molecular Biology Reports] Researchers aimed to clarify the regulatory roles of the SOX2/Notch axis in CRPC. They conducted immunohistochemistry analyses to evaluate SOX2, Notch, and Hey1 expression in the prostate cancer and CRPC tissues.

Prostate Cancer Immunotherapy: Improving Clinical Outcomes With a Multi-Pronged Approach

[Cell Reports Medicine] Scientists provide a summary of the status of immunotherapy in treating prostate cancer, with a discussion of multiple immune modalities, including vaccines, adoptively transferred T cells, and bispecific T cell engagers.

Recent Insights on the Clinical, Pathological, and Molecular Features of Intraductal Carcinoma of the Prostate

[International Journal Of Urology] Investigators summarize and outline the clinical and pathological features, differential diagnosis, molecular aspects, and management of intraductal carcinoma of the prostate, as described in previous studies.

Published since 2010, Prostate Cell News compiles top scientific journal articles covering the characterization, behavior, and culturing of prostate cells. Additionally, our editorial team curates the latest press releases, technical advances, jobs, and events relevant to the prostate cell research community. Prostate Cell News saves scientists valuable time while keeping them informed in their field, facilitating the rapid exchange of cutting edge research updates and science news.