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Prostate Cell News is an online resource summarizing the latest prostate cell research.
Curium Announces Strategic Partnership with PeptiDream for Prostate Cancer Theranostics in Japan
[Curium] Curium announced that it has entered into a strategic partnership with PDRadiopharma, Inc, a wholly-owned subsidiary of PeptiDream, for the clinical development, regulatory filing, and commercialization in Japan of 177Lu-PSMA-I&T and 64Cu-PSMA-I&T.
UK Black Men Are 2.5 Times As Likely To Die From Prostate Cancer
[Forbes] A “dangerously biased” combination of social factors and inadequate research is raising Black men’s already-heightened risk of developing prostate cancer, a UK charity has stated
Evaluating 4Kscore’s Role in Predicting Progression on Active Surveillance for Prostate Cancer Independently of Clinical Information and PIRADS Score
[Prostate Cancer and Prostatic Diseases] This was a single-institution, single-arm, non-therapeutic, interventional trial of 166 men with biopsy-confirmed prostate cancer enrolled between 2014–2020. Patients were placed on a trial-mandated AS protocol including yearly multiparametric MRI, prostate biopsy, and 4Kscore followed for 48 months after diagnosis.
PDIA2 Is Associated with the Prognosis of Prostate Cancer, and Downregulation of PDIA2 Delays the Progression of Prostate Cancer Cells
[Scientific Reports] Patients with prostate cancer who express PDIA2 high in particular have a bad prognosis in terms of progression-free survival. In addition, the upregulation of PDIA2 expression in prostate cancer patients was accompanied by higher Gleason scores, advanced tumor staging, lymph node metastasis, and elevated PSA levels.
Biological Functions and Molecular Mechanisms of LINC01116 in Cancer
[Heliyon] Scientists summarize the current evidence regarding the biological functions and molecular mechanisms of LINC01116 in the progression of cancer, providing theoretical references for LINC01116-related cancer treatment in the future.
Nivolumab in Patients with Metastatic Castration-Resistant Prostate Cancer with and without DNA Repair Defects
[Clinical Cancer Research] Scientists conducted a Phase II, multi-center, single-arm trial evaluating nivolumab in post-docetaxel metastatic castration-resistant prostate cancer patients. DNA repair defects was assessed using circulating tumor DNA.
Heterogeneous Genetic Architectures of Prostate Cancer Susceptibility in Sub-Saharan Africa
[Nature Genetics] The authors used genomic data from 3,963 cases and 3,509 controls from Ghana, Nigeria, Senegal, South Africa and Uganda to infer ancestry-specific genetic architectures and fine-map disease associations.
Integrated Multi-Omics Assessment of Lineage Plasticity in a Prostate Cancer Patient with Brain and Dural Metastases
[NPJ Precision Oncology] Researchers describe a patient with two treatment-emergent metastatic lesions, one to the brain with neuroendocrine prostate cancer histology and one to the dural membrane of adenocarcinoma histology. They performed genomic, transcriptomic, and proteomic characterization of these lesions and the primary tumor to investigate molecular features promoting these metastases.
PDIA2 Is Associated with the Prognosis of Prostate Cancer, and Downregulation of PDIA2 Delays the Progression of Prostate Cancer Cells
Patients with prostate cancer who express PDIA2 high in particular have a bad prognosis in terms of progression-free survival. In addition, the upregulation of...
Evaluating 4Kscore’s Role in Predicting Progression on Active Surveillance for Prostate Cancer Independently of Clinical Information and PIRADS Score
This was a single-institution, single-arm, non-therapeutic, interventional trial of 166 men with biopsy-confirmed prostate cancer enrolled between 2014–2020. Patients were placed on a trial-mandated...
Proteomic and Phosphoproteomic Landscape of Localized Prostate Cancer Unveils Distinct Molecular Subtypes and Insights Iito Precision Therapeutics
[Proceedings of The National Academy of Sciences of The United States of America] Investigators identified three distinct proteomic subtypes with significant difference in both molecular features and clinical prognosis.
Nuclear Receptor TLX Functions to Promote Cancer Stemness and EMT in Prostate Cancer via Its Direct Transactivation of CD44 and Stem Cell-Regulatory Transcription Factors
[British Journal of Cancer] Prostate cancer stem cells were isolated from various prostate cancer cell lines and clinical tumour tissues using multiple methods for various in vitro and in vivo oncogenic growth analyses.
Published since 2010, Prostate Cell News compiles top scientific journal articles covering the characterization, behavior, and culturing of prostate cells. Additionally, our editorial team curates the latest press releases, technical advances, jobs, and events relevant to the prostate cell research community. Prostate Cell News saves scientists valuable time while keeping them informed in their field, facilitating the rapid exchange of cutting edge research updates and science news.
