Intestinal Cell News

Intestinal Cell News is an online resource that curates the latest research using intestinal cells.

Abortive PDCoV Infection Triggers Wnt/β-catenin Pathway Activation, Enhancing Intestinal Stem Cell Self-Renewal, and Promoting Chicken Resistance

March 31, 2025

[Journal of Virology] Using chicken intestinal organoid monolayers, researchers found that although porcine deltacoronavirus infected them nearly as well as porcine intestinal organoid monolayers, infection did not result in detectable amounts of progeny virus.

The Histone Modifier KAT2A Presents a Selective Target in a Subset of Well-Differentiated Microsatellite-Stable Colorectal Cancers

March 28, 2025

[Cell Death & Differentiation] Investigators elucidated the molecular underpinnings of lysine acetyltransferase 2 A (KAT2A) dependency in CRC and assessed the consequences of KAT2A depletion.

Diosmin Alleviates Colitis by Inhibiting PANoptosis of Intestinal Epithelial Cells and Regulating Gut Microbiota and Metabolites

March 28, 2025

[Phytomedicine] Scientists investigate the therapeutic efficacy and mechanistic underpinnings of diosmin in dextran sulfate sodium-induced colitis, with a focus on its effects on intestinal epithelial cell PANoptosis, gut microbiota composition, fecal metabolites, and an in vitro inflammatory model using human colonic epithelial cells.

Effects of 1,3-Dioleoyl-2-palmitoylglycerol on Intestine Structural and Functional Development in Early Life

March 28, 2025

[Molecular Nutrition & Food Research] Researchers explored the effects of 1,3-Dioleoyl-2-palmitoyl-glycerol on intestinal epithelial structure and barrier construction in neonatal mice and the involvement of intestinal microorganisms.

Abortive PDCoV Infection Triggers Wnt/β-catenin Pathway Activation, Enhancing Intestinal Stem Cell Self-Renewal, and Promoting Chicken Resistance

March 28, 2025

Intestinal IL-25 Prevents High-Fat Diet-Induced Obesity by Modulating the Cholesterol Transporter NPC1L1 Expression in the Intestinal Epithelial Cells

March 28, 2025

[Scientific Reports] Given that the epithelial cell-derived cytokine IL-25 has been demonstrated to regulate metabolic disorders, researchers sought to examine the role of intestinal IL-25 in modulating a high-fat diet-induced obesity.

Inulin Protects Caco-2 Cells Against Lipopolysaccharide-Induced Epithelial Barrier Dysfunction

March 28, 2025

[Food Science & Nutrition] Scientists investigated the therapeutic effects of inulin, a prebiotic dietary fiber, in attenuating lipopolysaccharide-induced intestinal epithelial barrier dysfunction.

Gut Virome and Its Implications in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease

March 28, 2025

[BMC Medicine] The authors reviewed the composition of the gut virome in both healthy individuals and IBD patients, emphasizing the key viruses implicated in the onset and progression of IBD.

City of Hope Opens Phase I Clinical Trial Aiming to One Day Transform Rectal Cancer Into a Disease Treatable with Radiation Therapy to Avoid...

March 28, 2025

[City of Hope (Business Wire)] City of Hope® opened a Phase I trial seeking to one day transform rectal cancer from a mostly radiation-resistant disease to one that can be cured using radiation and chemotherapy.

Growth of the Maternal Intestine during Reproduction

March 20, 2025

[Cell] Using the mouse intestine, a striking and tractable model of organ resizing, researchers found that reproductive remodeling was anticipatory and distinct from diet- or microbiota-induced resizing.

PTK6 Drives HNRNPH1 Phase Separation to Activate Autophagy and Suppress Apoptosis in Colorectal Cancer

March 19, 2025

[Autophagy] Researchers discovered that protein tyrosine kinase 6 (PTK6) could activate autophagy and inhibit colorectal cancer apoptosis.

Comprehensive Metabolomic and Epigenomic Characterization of Microsatellite Stable BRAF-Mutated Colorectal Cancer

March 18, 2025

[Oncogene] The authors characterized the metabolomic, epigenetic, and transcriptomic patterns of altogether 39 microsatellite stable BRAF-mutated colorectal cancers.

Since 2015, Intestinal Cell News has been a valuable resource for keeping researchers and medical professionals updated on the latest publications, news and events in the field of gastrointestinal cell biology. Our editorial team collects and publishes the most current articles and reviews using stomach, colon, and small and large intestinal cells. We cover topics including the culturing of intestinal cells, intestinal organoids, intestinal cancers, and gastrointestinal conditions such as irritable bowel syndrome and Crohn’s disease.