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Mesenchymal Cell News
Mesenchymal Cell News is an online resource that delivers updates on the latest research in the mesenchymal stem cell field.
LncRNA HOXA-AS3 Promotes Cell Proliferation and Invasion via Targeting miR-218-5p/FOXP1 Axis in Osteosarcoma
[Scientific Reports] Investigators utilized several cellular biological strategies and molecular approaches to explore the biological functions and mechanisms of lncRNA HOXA-AS3 in osteosarcoma cells.
The Role of Mesenchymal Stem Cells in the Treatment and Pathogenesis of Psoriasis
[Cytokine] Investigators explore the current knowledge of psoriasis’s origins and the potential utilization of MSCs and their extracellular vesicles, particularly exosomes, in managing the condition.
What Kamala Harris’s Historic Bid for the US Presidency Means for Science
[Nature] The daughter of a scientist and a supporter of diversity in STEM, Harris’s prospects have stirred optimism among scientists.
RhoA/ROCK-TAZ Axis Regulates Bone Formation within Calvarial Trans-Sutural Distraction Osteogenesis
[Cellular Signalling] Scientists utilized pre-osteoblast-specific Ras homolog gene family member A (RhoA) deletion mice to establish an in vivo calvarial trans-sutural distraction model and an in vitro mechanical stretch model for pre-osteoblasts isolated from neonatal mice.
Human Mesenchymal Stromal Cells Inhibit Mycobacterium avium Replication in Clinically Relevant Models of Lung Infection
[Thorax] Human monocyte-derived macrophages were infected with M. avium Chester strain and treated with human bone marrow-derived MSCs.
Modified Mesenchymal Stromal Cells by In Vitro Transcribed mRNA: A Therapeutic Strategy for Hepatocellular Carcinoma
[Current Stem Cell Research & Therapy] Scientists generated modified MSCs by IVT mRNA transfection to overexpress granulocyte-macrophage colony-stimulating factor and determine their therapeutic effect alone or in combination with doxorubicin in a murine model of hepatocellular carcinoma.
The Safety and Efficacy of Adipose Tissue-Derived Exosomes in Treating Mild to Moderate Plaque Psoriasis: A Clinical Study
[Life Sciences] Researchers isolated exosomes from Mesenchymal Stem Cells(MSCs) of healthy adipose tissue using ultracentrifugation. 12 patients with plaque psoriasis were divided into three groups and given single doses of exosomes.
Efficacy of Stem Cells Versus Microvesicles in Ameliorating Chronic Renal Injury in Rats (Histological and Biochemical Study)
[Scientific Reports] Scientists evaluated the therapeutic potential of adipose tissue-derived stem cells in comparison to their microvesicles in aluminum chloride-induced chronic renal injury.
Evaluating [225Ac]Ac-FAPI-46 for the Treatment of Soft-Tissue Sarcoma in Mice
[European Journal of Nuclear Medicine and Molecular Imaging] The authors investigated the anti-tumor efficacy of [225Ac]Ac-FAPI-46 as monotherapy or in combination with immune checkpoint blockade (ICB) in immunocompetent murine models of sarcoma sensitive or resistant to ICB.
Transplantation of Human Endometrial Perivascular Stem Cells with Hydroxy Saffron Yellow a Promotes Uterine Repair in Rats
[Stem Cell Research & Therapy] Researchers observed whether the combination of endometrial perivascular cells with hydroxysafflor yellow A could improve the blood supply and fertility in the rat uterus after full-thickness injury.
Resin-Based Dental Pulp Capping Restoration Enclosing Silica and Portlandite Nanoparticles from Natural Resources
[Scientific Reports] Resin pulp capping restoration enclosing strengthening silica and bioactive portlandite nanofillers were prepared from industrial wastes. Silica nanoparticles were isolated from rice husk by heat treatment, followed by dissolution/precipitation treatment.
DiPRO1 Distinctly Reprograms Muscle and Mesenchymal Cancer Cells
[EMBO Molecular Medicine] Investigators provided substantial evidence of its role in the differentiation and proliferation of human myoblasts. Death, Differentiation, and PROliferation related PROtein 1 (DiPRO1) operated through the regulatory binding regions of SIX1, a master regulator of myogenesis.
Mesenchymal Cell News covers topics such as the isolation, identification, and culturing conditions of mesenchymal stem cells, as well as their cellular characterization, behavior and differentiation capacities. We also include research that focuses on identifying tissue sources of mesenchymal stem cells and their potential therapeutic applications in regenerative medicine and cellular therapies.
