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Mammary Cell News
Mammary Cell News is an online resource covering the latest research into breast cancer and mammary cells.
Dietary Fructose Enhances Tumor Growth Indirectly via Interorgan Lipid Transfer
[Nature] Scientists discovered that fructose supplementation enhanced tumour growth in animal models of melanoma, breast cancer, and cervical cancer without causing weight gain or insulin resistance.
Pirfenidone Promotes Cell Cycle Arrest and Apoptosis of Triple-Negative Breast Cancer Cells by Suppressing Hedgehog/GLI1 Signaling
[Naunyn-Schmiedebergs Archives of Pharmacology] Investigators elucidated the effects of pirfenidone, a FDA-approved oral anti-fibrotic drug which has recently shown antitumor potential, in the progression of TNBC and the underlying mechanisms.
NF-κB Associated Markers of Prognosis in Early and Metastatic Triple Negative Breast Cancer
[Breast Cancer Research] Scientists highlighted the potential role for NF-κB-associated factors, specifically lymphotoxin beta to be used as prognostic markers in TNBC, which could ultimately provide insight for improved targeted treatment approaches in the clinic.
The Potential Role of Targeting the Leptin Receptor as a Treatment for Breast Cancer in the Context of Hyperleptinemia: A Literature Review
The authors highlight the potential of targeting the leptin receptor and its cellular signaling in suppressing breast cancer progression.
[Naunyn-Schmiedebergs Archives of Pharmacology] Abstract
Peroxynitrite-Responsive Near-Infrared Fluorescent Imaging Guided Synergistic Chemo-Photodynamic Therapy via Biomimetic Metal–Organic Frameworks
[ACS Applied Materials & Interfaces] Investigators designed a biomimetic fluorescent nanoplatform which comprises tetrakis(4-carboxyphenyl) porphyrin and curcumin encapsulated within a zeolitic imidazolate framework-8, which was coated with a mouse breast cancer cell membrane for enhanced biocompatibility and targeting, while evading immune clearance.
Functionalizing of Magnetic Nanoparticles As Nano-Architecture Towards Bioimaging and Colorimetric Recognition of MCF-7 Cells: Dual Opto-Sensing and Fluorescence Monitoring for Early-Stage Diagnosis of Breast...
[Microchimica Acta] Investigators presented an innovative colorimetric and fluorescence bioimaging platform towards MCF-7 using folic acid-conjugated iron-oxide magnetite silica-based nanocomposite.
Imatinib Impedes EMT and Notch signaling by Inhibiting p300 Acetyltransferase in Breast Cancer Cells
[Molecular Carcinogenesis] Scientists highlighted the ability of Imatinib to suppress epithelial-mesenchymal transition through modulation of the Notch signaling pathway, offering a novel therapeutic avenue for breast cancer treatment.
Evaluating the Combined Estrogenic Effects of Plant Growth Regulators via Electrochemical and E-Screen Methods
[RSC Advances] Researchers used electrochemical methods to investigate the electrochemical behavior and estrogenic effects of plant growth regulators gibberellic acid, ethylene, and naphthalene acetic acid on estrogen-free human breast cancer cells cells when exposed individually or in combination.
Anti-Tumor Activity and Biomarker Analysis for TROP2-Antibody Drug Conjugate Datopotamab Deruxtecan in Patient-Derived Breast Cancer Xenograft Models
[Clinical Cancer Research] Scientists tested the activity of datopotamab deruxtecan in a panel of breast cancer patient-derived xenografts varying in TROP2 expression.
Childhood, Adolescent and Young Adulthood Cancer Risk in BRCA1 or BRCA2 Pathogenic Variant Carriers
[JNCI-Journal of The National Cancer Institute] Investigators evaluated this risk and to inform clinical care of young BRCA1/2 PV carriers and genetic testing for CAYA cancer patients.
Breast Cancer Subtype-Specific Organotropism is Dictated by FOXF2-Regulated Metastatic Dormancy and Recovery
[Cancer Research] The authors found that FOXF2 promoted the seeding and proliferative recovery from dormancy of luminal breast cancer and basal-like breast cancer cells in the bone by activating the NF-κB and BMP signaling pathways.
Novartis Kisqali® Receives European Commission Approval in a Broad Population of Patients with HR+/HER2- Early Breast Cancer at High Risk of Recurrence
[Novartis] Novartis announced that the European Commission has approved Kisqali® in combination with an aromatase inhibitor for the adjuvant treatment of patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative early breast cancer at high risk of recurrence
For over a decade, Mammary Cell News has been keeping the global scientific and medical communities informed about the latest research, reviews, and news in the field of mammary tissues. Our editors gather publications on the topic of mammary cell differentiation and characterization, as well as the progression and treatment of breast cancer. We also keep scientists up-to-date on the latest policy changes, job postings, and events.
