Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Immunology of Infectious Disease News
Immunology of Infectious Disease News is an online resource dedicated to covering the latest research and developments in the field of infectious diseases.
A Robust Mouse Model of HPIV-3 Infection and Efficacy of GS-441524 against Virus-Induced Lung Pathology
[Nature Communications] By multiplex fluorescence RNAscope and immunohistochemistry followed by confocal microscopy, the authors demonstrated viral tropism to ciliated cells and club cells of the bronchiolar epithelium.
Prion Protein Alters Viral Control and Enhances Pathology after Perinatal Cytomegalovirus Infection
[Nature Communications] Using a murine model, investigators showed the role of prion protein in tempering neonatal T cell immunity during cytomegalovirus infection.
Emergent BioSolutions’ ACAM2000®, (Smallpox and Mpox (Vaccinia) Vaccine, Live) Receives US FDA Approval for Mpox Indication; Public Health Mpox Outbreak Continues across Africa...
[Emergent BioSolutions Inc.] Emergent BioSolutions Inc. announced that the US FDA has approved the supplemental Biologics License Application for the expansion of the indication for ACAM2000® to include prevention of mpox disease in individuals determined to be at high risk for mpox infection.
Comparison of Protection against Mpox Following mRNA or Modified Vaccinia Ankara Vaccination in Nonhuman Primates
[Cell] mRNA-1769, an mRNA-lipid nanoparticle vaccine expressing mpox virus (MPXV) surface proteins, was tested in a lethal MPXV primate model.
Germline-Targeting HIV Vaccination Induces Neutralizing Antibodies to the CD4 Binding Site
[Science Immunology] Researchers described how germline-targeting immunogen BG505 SOSIP germline trimer 1.1, generated through structure-based design, engaged a diverse range of VRC01-class broadly neutralizing antibody precursors.
Lipid and Glucose Profiles in Pregnant Women with HIV on Tenofovir-Based Antiretroviral Therapy
[Clinical Infectious Diseases] Scientists analyzed data within the IMPAACT 2010/VESTED trial, which demonstrated better pregnancy outcomes in pregnant women randomized to initiate Tenofovir alafenamide/Emtricitabine (FTC)+Dolutegravir (DTG) or tenofovir disoproxil fumarate/FTC+DTG.
EXTL3 and NPC1 Are Mammalian Host Factors for Autographa californica Multiple Nucleopolyhedrovirus Infection
[Nature Communications] The authors employed a cell surface protein-focused CRISPR screen to identify host dependency factors for baculovirus transduction in mammalian cells.
Delivery of US28 by Incoming HCMV Particles Rapidly Attenuates Akt Activity to Suppress HCMV Lytic Replication in Monocytes
[Science Signaling] Scientists investigated the mechanisms through which human cytomegalovirus established a quiescent infection in monocytes.
Fecal Let-7b and miR-21 Directly Modulate the Intestinal Microbiota, Driving Chronic Inflammation
[Gut Microbes] Using an in vitro microbiota modeling system, researchers revealed that fecal let-7b and miR-21 could directly modify the composition and function of complex human microbiota, increasing their proinflammatory potential.
The Dual Role of Ribosomal Protein SA in Pathogen Infection: The Key Role of Structure and Localization
[Molecular Biology Reports] Investigators comprehensively examine the dual role of ribosomal protein SA in pathogen infection by analyzing its structural domains, localization, and interactions with cellular and pathogen molecules.
NSF Invests $72 Million In Four University Pandemic Research Centers
[Forbes] The US National Science Foundation is investing a total of $72 million to establish four multi-university research centers that will conduct research on the prediction and prevention of pandemics as well as train the next generation of scientists to continue such work.
Tuberculosis in Otherwise Healthy Adults with Inherited TNF Deficiency
[Nature] Researchers reported two adults with recurrent pulmonary tuberculosis who were homozygous for a private loss-of-function TNF variant. Neither has any other clinical phenotype and both mount normal clinical and biological inflammatory responses.
Immunology of Infectious Disease News was founded to keep the scientific community current with the latest developments in infectious disease research. We feature high-impact publications, news, jobs, and events focused on immune responses to and the development of treatments for infectious diseases such as COVID-19, HIV, hepatitis, tuberculosis, influenza, and malaria.
