Pulmonary Cell News

Pulmonary Cell News is an online resource dedicated to the topics of respiratory disease, lung cancer, and pulmonary cells.

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Hydrogel-Based Airway-on-Tube With Perfusable Endothelial Lumen and Outward Epithelialization

March 12, 2026

[Advanced Materials] Investigators introduced an airway-on-tube that integrates an engineered ECM hydrogel, tuned to match lung tissue stiffness, with a tubular melt electrowritten scaffold.

Novocure Announces Optune Lua® Receives Reimbursement Approval in Japan for the Treatment of Non-Small Cell Lung Cancer

March 11, 2026

[Novocure] Novocure announced that Japan’s Ministry of Health, Labour and Welfare approved reimbursement for Optune Lua^® through the country’s National Health Insurance coverage.

Clu Transitional Alveolar Epithelial Cells Promote Lung Injury Repair and Fibrosis Progression

March 11, 2026

[British Journal of Pharmacology] Researchers investigated an intermediate subpopulation of alveolar epithelial cells, termed “Regeneration Alveolar Epithelial cells“, which reached a peak 14 days post-injury.

Targeting the Lipid Metabolism Proteins FASN and GPAM in Alveolar Type II Cells Decreases Lung Metastasis

March 11, 2026

[Cancer Discovery] Investigators discovered that breast cancer-derived lung metastases stimulate the proliferation of alveolar type II cells in their vicinity and reprogram them into lipid feeder cells in mice and patients using spatial analysis.

Pulmonary Surfactant Protein D Reduces Lung Cancer Progression Associated with Decreased IL-4/STAT6 Signaling

March 11, 2026

[NPJ Precision Oncology] Through integrative analysis of multimodal human data researchers demonstrated that the SP-D geneexpression is reduced to near absence in metastatic NSCLC tissue, linking its loss to metastatic progression.

TRMT6-Directed m1a Modification Initiates Lung Squamous Cell Carcinoma via YTHDF3-Stabilized Cell Cycle Genes

March 11, 2026

[NPJ Precision Oncology] Scientists delineated the N¹-Methyladenosine ( m¹A) regulatory network in lung squamous cell carcinoma (LUSC). The dominant m¹A writer of TRMT6 emerged as the most up-regulated regulator in LUSC through a comprehensive pan-cancer analysis.

miR-320a Enhances Radiosensitivity in Non-Small Cell Lung Cancer by Targeting RAD51 and Modulating Ferroptosis via GPX4

March 11, 2026

[Scientific Reports] The authors investigated how miR-320a regulates RAD51 to affect the radiosensitivity of NSCLC. miR-320a expression in NSCLC tissues and cell lines was evaluated using The Cancer Genome Atlas data and qRT-PCR.

Propofol Regulates METTL3-Mediated PARP-1 m6a Modification to Promote Parthanatos to Improve NSCLC Chemotherapy Resistance

March 11, 2026

[Scientific Reports] Researchers investigated the molecular mechanism by which propofol enhances chemosensitivity in NSCLC. In vitro experiments were performed to evaluate the effects of propofol on NSCLC cell lines and to elucidate the underlying molecular mechanisms.

Fueling the Fire: Metabolic Dysfunction and Senescence As Drivers of Lung Aging and Disease

March 11, 2026

[Physiological Reviews] Scientists explore the current knowledge of healthy lung aging, discuss which pathomechanisms in chronic lung disease are characterized by senescence, and summarize current target therapeutics and their impact on lung disease.

Lactylation in Pulmonary Fibrosis: Current Understanding and Challenges

March 11, 2026

[Journal of Translational Medicine] The authors summarize the potential pathways through which lactylation promotes pulmonary fibrosisThe au, based on the current sites and roles of lactylation in epithelial cells, fibroblasts, and macrophages.

Five Global Teams Awarded $125 Million to Take on the Toughest Challenges at the Frontiers of Cancer Science

March 6, 2026

[Cancer Grand Challenges (Business Wire)] Cancer Grand Challenges, a global initiative co-founded by the National Cancer Institute in the US and Cancer Research UK, announced a major $125m commitment to propel cancer research into uncharted territory.

Parathyroid Hormone-Related Protein Is a Therapeutic Target in Idiopathic Pulmonary Fibrosis

February 26, 2026

[Signal Transduction and Targeted Therapy] Researchers investigated the mechanistic role of parathyroid hormone–related protein_1-34 in pulmonary fibrosis both in vitro and using in vivo models and proposed different strategies for blocking idiopathic pulmonary fibrosis progression.

Spurred by advances in the modeling of the airway epithelium, Pulmonary Cell News was launched in 2012 to help scientists stay at the forefront of cutting edge research. Every week, our editors hand-select the most recent, top scientific journal articles on the topics of pulmonary cells, lung cancers, and respiratory diseases such as COPD and asthma. We also highlight current job postings and upcoming events to keep the global research community connected!