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Pulmonary Cell News
Pulmonary Cell News is an online resource dedicated to the topics of respiratory disease, lung cancer, and pulmonary cells.
MSU Researcher Awarded National Grant to Study Rare Childhood Lung Disease
[Michigan State University (MSU)] Ripla Arora received the Pulmonary Hypertension Association (PHA) Pediatric PH Research Award to expand on research she started over ten years ago while studying embryology. The $65K award from the PHA will enable Arora to delve deeper into the biology of TBX4 and TBX5 gene mutations.
Obtusifolin Mitigates Acute Lung Injury and Improves Cardio-Pulmonary Functions in Acute Lung Injury Model by Modulating Oxidative Stress and NF-κB Signaling.
[Naunyn-Schmiedebergs Archives of Pharmacology] Scientists investigated the therapeutic effects of obtusifolin against lipopolysaccharide-induced lung and cardiac inflammation/injury using both in vitro and in vivo models.
EGFR-TKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer
[Advanced Science] Two drug-tolerant persister lung cancer cells with different proliferative capacities were established and identified dipeptidyl peptidase 4 (DPP4) as a potential therapeutic target.
Unraveling the SOX11-IGF2 Signaling Axis in Early Lung Development: Implications for Lung Disease
[Communications Biology] Researchers delved into the role of SOX11 in early lung development using a Sox11 knockout mouse model.
RNA m6a Dynamics Promote Transcription and RNA Stability of Bivalent Genes during iPSC-Induced Generation of Human Lung Progenitors
[Cell Reports] The authors uncovered the dynamic and stage-specific patterns of the N6-methyladenosine (m6A) methylome that correlate with gene expression changes during the differentiation of hiPSCs into lung progenitors.
Neuroendocrine Cells Orchestrate Regeneration through Desert Hedgehog Signaling
[Cell] Researchers presented a mechanism wherein Desert hedgehog (Dhh), secreted from epithelial neuroendocrine cells, elicits a regenerative/protective response from mesenchymal cells.
Progress in the Application of Organoids for Exploring the Relationship between Macrophages and Various Lung Diseases
[Biofabrication] Investigators summarize the research progress on organoids in exploring macrophage involvement in pulmonary diseases.
Systemic In Utero Gene Editing As a Treatment for Cystic Fibrosis
[Proceedings of The National Academy of Sciences of The United States of America] Researchers demonstrated cystic fibrosis (CF) transmembrane conductance regulator gene correction in multiple tissues affected by CF after a single in utero administration of nanoparticles containing gene editing cargo.
Methylation of RBM39 by PRMT6 Enhances Resistance to Indisulam in Non-Small Cell Lung Cancer by Promoting Alternative Splicing of Proto-Oncogenes
[PLOS Biology] Scientists demonstrated that hypermethylation of RNA-binding protein 39 (RBM39), a specific target of Indisulam, is closely associated with Indisulam resistance. Protein arginine methyltransferase 6 (PRMT6) methylates RBM39 at R92.
Pelargonidin-3-O-galactoside Alleviates Acute Lung Injury Induced by Klebsiella pneumoniae by Targeting CD38-Mediated Pyroptosis
[Journal of Agricultural and Food Chemistry] Scientists explored the protective effects of pelargonidin-3-O-galactoside on Klebsiella pneumoniae-induced acute lung injury and its underlying mechanisms.
γδ+ T Cell-Derived IL-17A Stimulates Airway Epithelial/Stromal Cells to Secrete G-CSF, Promoting Lung-Specific Pathogenic Siglec-F+ Neutrophil Development in PPE-Induced Emphysema
[Cellular & Molecular Immunology] Scientists identified a distinct population of lung-specific pathogenic Siglec-F+ neutrophils in a porcine pancreatic elastase (PPE)-induced mouse model of emphysema.
Pulmonary Hazards of Nanoplastic Particles: A Study Using Polystyrene in In Vitro Models of the Alveolar and Bronchial Epithelium
[Journal of Nanobiotechnology] Researchers used model polystyrene nanoparticles doped with the fluorescent metal europium to enhance the understanding of nanoparticles hazard and investigates adverse outcomes associated with exposure in human lungs using alveolar and bronchial cell models grown.
Spurred by advances in the modeling of the airway epithelium, Pulmonary Cell News was launched in 2012 to help scientists stay at the forefront of cutting edge research. Every week, our editors hand-select the most recent, top scientific journal articles on the topics of pulmonary cells, lung cancers, and respiratory diseases such as COPD and asthma. We also highlight current job postings and upcoming events to keep the global research community connected!
