Organoid News

Organoid News is an online resource dedicated to the latest research about and featuring organoids.

Human BBB-Brain Organoid on a Millifluidic Plate for Modeling Brain Parenchymal Pathology-Induced Barrier Dysfunction

July 9, 2026

[Journal of Advanced Research] Researchers developed an integrated human blood–brain barrier (BBB)-brain organoid-on-a-chip model that replicates physiological interaction and pathological disruption between the BBB and brain parenchyma.

Core Binding Factor β Preserves Early Chondrogenic Identity and Prevents Hypertrophic Transition in Cartilage Organoids Formation

July 9, 2026

[Cell & Bioscience] Scientists identified core binding factor β as a critical regulator of early chondrogenic identity and a suppressor of hypertrophic transition during hiPSC-derived cartilage organoid formation.

Activation of KIT Signaling Promotes Early Tumorigenesis through the AP-1 Pathway in APC/TP53 Double-Knockout Human Colon Organoids

July 9, 2026

[Cell Death & Disease] Researchers identify an AP-1/KIT signaling axis that drives early colorectal tumorigenesis in APC/TP53-deficient human colon organoids, revealing a potential target for early intervention.

Early Cell-Autonomous and Niche-Mediated Epithelial Response to Influenza Infection in Primary Alveolar Organoids

July 9, 2026

[JCI Insight] The authors used primary alveolar organoids to uncover how influenza infection rapidly reprograms both infected and neighboring alveolar cells, revealing early epithelial responses linked to acute respiratory distress syndrome.

DLP Bioprinting of Cartilage Organoid-Laden Bioinks Yields High-Fidelity Auricular Constructs with Enhanced Chondrogenesis

July 9, 2026

[Stem Cell Research & Therapy] Investigators developed and validate a cartilage organoid-laden digital light processing (DLP) bioprinting strategy for auricular reconstruction and compared its performance with conventional chondrocyte-laden prints.

Zika Virus Infections of Human Stem Cell-Derived Cerebral Organoids Reveal Viral Lineage-Specific Pathogenesis Responses

July 9, 2026

[Mbio] Researchers performed systematic, side-by-side comparisons of African, Asian, and American Zika virus lineage infections using cerebral organoids derived from human embryonic stem cells, a relevant human model experimental system.

ERC Awards Proof of Concept Grants to 182 Researchers

July 6, 2026

[The European Research Council] The European Research Council (ERC) has announced the names of its grantees to be awarded the Proof of Concept Grants. Funding for this first round of 2026, worth €27.3 million, will go to 182 researchers.

Bioengineering Advances in Pancreatic Cancer Organoids for Reproducible Tumor Microenvironment Modeling

June 30, 2026

[iScience] The authors synthesize recent bioengineering advances that upgrade pancreatic cancer patient-derived organoid platforms across three interconnected dimensions.

Three OeAW Researchers Receive ERC Advanced Grants

June 25, 2026

[Austrian Academy of Siences] The European Research Council (ERC) has awarded its most prestigious grants to Christoph Bock, Irene Forstner-Müller, and Jürgen Knoblich - a triple success for the Austrian Academy of Sciences (OeAW).

Host-Virus Determinants of Ebola Virus Persistence in a Human Cerebral Organoid Model

June 25, 2026

[Nature Microbiology] Investigators developed a human cerebral organoid model to investigate the host and viral determinants of Ebola virus central nervous system persistence.

Organoid Modeling of Lung Branching Morphogenesis and Epithelial Lineage Specification

June 25, 2026

[Developmental Cell] Scientists reported a multilevel branching lung organoid model generated from primary tip epithelial cells using a robust, chemically defined protocol.

A 3D Pooled PBMC-Organoid Co-Culture Platform for Profiling Immune Susceptibility and PD-1 Blockade Response in Gastric Cancer

June 25, 2026

[BMC Medicine] The authors established a standardized allogeneic 3D co-culture platform integrating patient-derived peritoneal metastatic gastric cancer organoids with pooled peripheral blood mononuclear cells from healthy donors.

Organoids are three-dimensional cell cultures that more accurately model cell behavior, organ function, and pathology than traditional two-dimensional cell culture. Organoid News was launched in 2020 to help scientists stay up-to-date with this revolutionary new research system. Use Organoid News to stay current with the latest applications and discoveries using organoids, as well as new reviews, jobs, news, and upcoming events.