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Organoid News
Organoid News is an online resource dedicated to the latest research about and featuring organoids.
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Cardiopedia-Ligand: A Ligand-Receptor Perturbation Atlas of Human Cardiac Organoid Function and Transcriptional State
[Cell Stem Cell] Researchers established Cardiopedia-Ligand, a comprehensive perturbation-function-transcriptome atlas generated by stimulating human cardiac organoids with 87 ligands targeting 98 cell-membrane receptors expressed in the human heart.
Porcine Airway Organoids Reveal Strain-Associated Replication and Epithelial Host Response Signatures of a Reassortant H1N1 Virus
[Emerging Microbes & Infections] Investigators established long-term expanding three-dimensional porcine airway organoids as a platform for the phenotypic and transcriptomic characterization of reassortant influenza viruses.
Leveraging IGF Signaling to Improve the Spatial Organization and Regenerative Potential of iPSC-Derived Vascularized Liver Organoids
[Science Advances] Scientists developed vascularized liver organoids by integrating hiPSC–derived hepatoblasts and endothelial cells into decellularized scaffolds functionalized with an anti-CD31 aptamer–based vascular coating agent.
Expanded GEP-NET Organoid Culture for Personalized Therapy Evaluation
[Science Advances] In this study, patient tumor organoids were generated from 35 tumors of pancreatic, small intestinal, and gastric origin, obtained from 17 patients.
Tumor Microenvironment-Simulated Organoids for Personalized Therapy Prediction in Head and Neck Squamous Cell Carcinoma
[Oncogene] The authors established a total of 30 patient-derived organoids from 79 patients with locally advanced and recurrent/metastatic head and neck squamous cell carcinoma.
Msh2 Depletion Impairs Cell Differentiation, Proliferation, and Metabolism in Esophageal Organoids
[Journal of Cell Science] Researchers aimed to evaluate the effects of MutS Homolog 2 (Msh2) loss on stem cell functions, including differentiation, clonogenicity, and proliferation, in murine esophageal organoids.
AcroCyte Therapeutics Awarded ARPA ‑H Funding to Advance Scalable Human Organoid Technologies
[AcroCyte Therapeutics, Inc.] AcroCyte Therapeutics, Inc. announced that it has been selected to receive funding from the Advanced Research Projects Agency for Health (ARPA‑H) to advance scalable human organoid technologies for regenerative medicine applications.
Miriam Filippi receives IEEE EMBS Early Career Achievement Award 2026
[Eidgenössische Technische Hochschule Zürich] Miriam Filippi, Senior Researcher at the Soft Robotics Lab in the Department of Mechanical and Process Engineering, has been awarded the IEEE EMBS Early Career Achievement Award 2026.
Progressing Regenerative Medicine: Integrating Bioprinting Platforms for Stem Cell Applications
[Stem Cell International] Investigators critically evaluate bioprinting strategies tailored for stem cell applications, including the selection of stem cell sources, bioink formulation, crosslinking methodologies, and dynamic culture systems.
AcroCyte Therapeutics Awarded ARPA ‑H Funding to Advance Scalable Human Organoid Technologies
[AcroCyte Therapeutics, Inc.] AcroCyte Therapeutics Inc. today that it has been selected to receive funding from the Advanced Research Projects Agency for Health (ARPA‑H) to advance scalable human organoid technologies for regenerative medicine applications.
Mapping Mesenchymal Diversity in the Human Small Intestine and Organoids
[Nature Cell Biology] Investigators leveraged single-cell RNA-sequencing data to build a Xenium spatial transcriptomics gene panel covering the cell diversity of the human small intestine. They leveraged this high-resolution atlas to interrogate cell–cell signaling and benchmark PSC-derived human intestinal organoids.
Subcutaneous Transplantation of Lung Organoids Ameliorates Vascular Dementia via the IGFBP7-Ago2 Mediated Lung-Brain Axis
[Journal of Neuroinflammation] Scientists demonstrated that subcutaneous transplantation of lung organoids ameliorated cognitive dysfunction in a mouse model of bilateral common carotid artery stenosis.
Organoids are three-dimensional cell cultures that more accurately model cell behavior, organ function, and pathology than traditional two-dimensional cell culture. Organoid News was launched in 2020 to help scientists stay up-to-date with this revolutionary new research system. Use Organoid News to stay current with the latest applications and discoveries using organoids, as well as new reviews, jobs, news, and upcoming events.
